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# Tus%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520qd
## Overview
Tus%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520qd is a cough suppressant (antitussive).
## Primary Indications
Suppression of chronic cough.
## Adult Dosing
The typical dose is 15-30 mg every 4-6 hours as needed. The maximum daily dose is generally 120 mg.
## Pediatric Dosing
Dosing in pediatric patients is not well-established and should be guided by local protocols or specialist consultation. Some sources suggest doses around 1 mg/kg/day divided into 3-4 doses, but this requires careful consideration of age and weight.
## Dose Adjustments
No specific dose adjustments are typically required for hepatic or renal impairment, but caution and close monitoring are advised, especially in severe dysfunction.
## Contraindications
Hypersensitivity to tus%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520qd. Use with caution in patients with significant respiratory depression.
## Adverse Effects
Common adverse effects include dizziness, drowsiness, nausea, and vomiting. Less common effects may include constipation, headache, and confusion.
## Key Drug Interactions
* **CNS Depressants (e.g., opioids, benzodiazepines, alcohol):** Increased risk of sedation and respiratory depression.
* **MAOIs:** Theoretical risk of hypertensive crisis, though less common with non-opiate antitussives.
## Monitoring
Monitor for effectiveness in cough suppression and for signs of adverse effects, particularly sedation and respiratory depression.
## Clinical Pearls
Tus%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520qd should be used cautiously in patients with a history of substance abuse. It is generally not recommended for productive coughs where sputum clearance is desired.
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*Disclaimer: This information is intended for healthcare professionals. Always consult the current prescribing information and relevant guidelines before making clinical decisions.*
