Tab%252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520voihep

## Tab%252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520voihep ### Overview This drug is a nucleoside analog used in the treatment of chronic hepatitis B virus (HBV) infection. ### Primary Indications Chronic hepatitis B infection. ### Adult Dosing The standard dose is 0.5 mg orally once daily. ### Pediatric Dosing Dosing in pediatric patients is not established. ### Dose Adjustments Dose adjustment is recommended in patients with moderate to severe renal impairment. Specific recommendations depend on the calculated creatinine clearance. ### Contraindications Hypersensitivity to the active ingredient or any excipient. ### Adverse Effects Common adverse effects include nausea, vomiting, diarrhea, headache, and fatigue. Lactic acidosis and severe hepatomegaly with steatosis (including hepatic failure) have been reported. ### Key Drug Interactions No significant drug interactions are expected, but caution is advised with coadministration of drugs that are renally excreted, as this agent is also renally excreted. ### Monitoring Monitor liver function tests, HBV DNA levels, and renal function regularly. Monitor for signs and symptoms of lactic acidosis and liver decompensation. ### Clinical Pearls Ensure adequate contraception for both male and female patients during and for a period after treatment. Do not use in patients with decompensated cirrhosis. *** *Disclaimer: This information is intended for healthcare professionals. Always consult the most current prescribing information and institutional protocols before making treatment decisions.*