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# Miconazole Vaginal Pessary ## Overview Miconazole is an imidazole antifungal agent that inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. The vaginal pessary formulation is designed for localized treatment of vaginal yeast infections. ## Primary Indications Vulvovaginal candidiasis (yeast infection). ## Adult Dosing **Intravaginal:** * **100 mg pessary:** Insert 1 pessary vaginally at bedtime for 7 days. * **200 mg pessary:** Insert 1 pessary vaginally at bedtime for 3 days. * **100 mg vaginal suppository:** Insert 1 suppository vaginally at bedtime for 7 days. * **200 mg vaginal suppository:** Insert 1 suppository vaginally at bedtime for 3 days. * **1% vaginal cream (applicator):** 5 grams (full applicator) inserted vaginally at bedtime for 7 days. * **4% vaginal cream (applicator):** 5 grams (full applicator) inserted vaginally at bedtime for 3 days. *Note: Specific duration of therapy may vary based on product availability and prescriber preference.* ## Pediatric Dosing Dosing for pediatric patients is not well-established for the vaginal pessary formulation. Consultation with a pediatrician or infectious disease specialist is recommended for appropriate