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# Magnesium Sulfate
## Overview
Magnesium sulfate is an electrolyte used to treat and prevent hypomagnesemia and to manage various obstetric and cardiac conditions. It can be administered intravenously (IV) or intramuscularly (IM).
## Primary Indications
* Hypomagnesemia
* Eclampsia and pre-eclampsia
* Torsades de pointes
* Bronchospasm (adjunctive therapy)
* Severe asthma exacerbations (adjunctive therapy)
## Adult Dosing
* **Hypomagnesemia:**
* **Severe deficiency:** 4-6 grams IV initially, followed by 2-4 grams every 4-12 hours as needed.
* **Mild to moderate deficiency:** 1 gram IM every 6 hours for 4 doses, or 5 grams in 500 mL D5W or NS IV over 3 hours.
* **Maintenance:** Typically 2-6 grams IV per 24 hours, adjusted based on serum magnesium levels.
* **Eclampsia/Pre-eclampsia prophylaxis and treatment:** Loading dose of 4-6 grams IV over 5-20 minutes, followed by a continuous infusion of 1-2 grams per hour. May use IM doses in obstetrics (e.g.,
