Liquid%2525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

## Liquid Paraffin ### Overview Liquid paraffin is a mineral oil used as a lubricant and laxative. It works by coating the stool, making it softer and easier to pass. ### Primary Indications * Constipation ### Adult Dosing * **Laxative:** 10 mL to 30 mL orally once daily, usually at bedtime. Doses may vary based on product concentration and individual response. ### Pediatric Dosing * **Constipation:** * **1-6 years:** 5 mL orally once daily. * **6-12 years:** 10 mL orally once daily. * Dosing for children under 1 year is generally not recommended without physician guidance. * Maximum daily dose for children should not exceed 10 mL for those under 6 years and 20 mL for those aged 6-12 years. ### Dose Adjustments * No dose adjustments are typically required for renal or hepatic impairment. ### Contraindications * Appendicitis or undiagnosed abdominal pain. * Intestinal obstruction. * Fecal impaction. * Individuals with difficulty swallowing, due to risk of lipid pneumonia from aspiration. ### Adverse Effects * Diarrhea * Abdominal cramping * Nausea * Anal leakage (especially with higher doses) * Lipid pneumonia (rare, but serious, with chronic aspiration) ### Key Drug Interactions * **Fat-soluble vitamins (A, D, E, K):** Liquid paraffin can impair the absorption of fat-soluble vitamins with chronic use. Consider separation of doses or vitamin supplementation if long-term use is anticipated. * **Other medications:** May decrease the absorption of other orally administered medications due to its oily nature and effect on gut motility. Separate administration by at least 2 hours. ### Monitoring * Bowel movements (frequency, consistency). * Signs of dehydration or electrolyte imbalance with excessive use. * Signs of aspiration if risk factors are present. ### Clinical Pearls * Administer at bedtime to minimize daytime anal leakage. * Avoid prolonged or excessive use, as it can lead to dependence and vitamin malabsorption. * Do not administer to individuals who are bedridden, elderly, or have a significant risk of aspiration. * Use with caution in pregnancy and breastfeeding; consult prescribing information. *** **Please consult the current prescribing information for the specific liquid paraffin product being used for complete and up-to-date details.**