Liquid%252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a highly refined mineral oil used as a lubricant and emollient. It acts as a laxative by softening stool and easing passage. ## Primary Indications * Constipation ## Adult Dosing * **Laxative:** 15 mL to 45 mL orally once daily or in divided doses. Higher doses may be used under medical supervision for more severe constipation. ## Pediatric Dosing * **Constipation:** Dosing varies by age and weight. Generally: * 1 to 5 years: 5 mL to 10 mL orally once daily. * 6 to 12 years: 10 mL to 15 mL orally once daily. * Over 12 years: As per adult dosing. * *Note: Specific pediatric dosing may depend on local hospital protocols or product labeling.* ## Dose Adjustments No dose adjustments are typically required for hepatic or renal impairment. ## Contraindications * Appendicitis or undiagnosed abdominal pain. * Intestinal obstruction. * Hypersensitivity to liquid paraffin. * Difficulty swallowing (risk of aspiration). ## Adverse Effects * **Common:** Abdominal cramping, bloating, diarrhea, anal leakage. * **Less Common/Serious:** * Lipoid pneumonia (if aspirated, particularly in the elderly or those with impaired swallowing). * Malabsorption of fat-soluble vitamins (with chronic, high-dose use). * Pruritus ani (anal itching). ## Key Drug Interactions * **Mineral Oil:** May reduce the absorption of fat-soluble vitamins (A, D, E, K) and certain medications, including digoxin, anticoagulants, and oral contraceptives, when taken concurrently. Separate administration by at least 2 hours. ## Monitoring * Monitor for bowel movements and stool consistency. * Assess for signs of anal leakage or perianal irritation. * In patients with risk factors for aspiration, monitor for respiratory symptoms. ## Clinical Pearls * Administer undiluted or mixed with water or juice. * Avoid administration immediately before lying down to reduce the risk of aspiration. * Long-term, habitual use can lead to dependence and interfere with nutrient absorption. * Caution in elderly patients and those with swallowing difficulties due to aspiration risk. *** *Please verify current prescribing information and institutional protocols for definitive guidance.*