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# Liquid Paraffin ## Overview Liquid paraffin is a mineral oil used as a laxative and emollient. It works by lubricating the intestinal walls, softening stool, and preventing water absorption from the feces. ## Primary Indications * Constipation * Skin conditions (e.g., dryness, eczema) as an emollient ## Adult Dosing * **Laxative:** 10-30 mL once daily, typically at bedtime. * **Emollient:** Apply thinly to affected skin areas as needed. ## Pediatric Dosing * **Laxative:** * Children 1-5 years: 5 mL once daily. * Children 6-12 years: 10 mL once daily. * Children over 12 years: Dosing as per adult. * Use in children under 1 year is generally not recommended without medical supervision due to the risk of aspiration. ## Dose Adjustments No specific dose adjustments are typically required for renal or hepatic impairment. ## Contraindications * Hypersensitivity to liquid paraffin. * Appendicitis or acute abdominal pain. * Intestinal obstruction. * Inability to swallow without risk of aspiration (particularly in infants and the elderly). ## Adverse Effects * Anal leakage (especially with higher doses). * Abdominal cramping. * Nausea. * Lipoid pneumonia (rare, associated with aspiration). * Reduced absorption of fat-soluble vitamins (A, D, E, K) with chronic, high-dose use. ## Key Drug Interactions * **Mineral oil can reduce the absorption of:** fat-soluble vitamins (A, D, E, K), anticoagulants (e.g., warfarin), and some cardiac glycosides. Dosing should be separated. ## Monitoring * Monitor for bowel movements and stool consistency. * Assess for anal leakage or signs of aspiration. * For long-term use, consider monitoring for vitamin deficiencies, especially in vulnerable populations. ## Clinical Pearls * Administer at bedtime to minimize daytime leakage. * Avoid prolonged use (generally no more than 1-2 weeks) due to potential for dependency and malabsorption. * Warn patients about the risk of slippery surfaces due to anal leakage. * Ensure adequate hydration when used as a laxative. * For emollient use, apply to damp skin for better absorption. *** *Disclaimer: This information is intended for healthcare professionals. Always consult the most current prescribing information and professional guidelines before making clinical decisions.*