Please check your internet connection and try again.
# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as an emollient and laxative. It works by lubricating the intestinal tract and softening stool.
## Primary Indications
* Constipation
## Adult Dosing
* **Laxative:** 10 mL to 30 mL by mouth once daily, typically at bedtime. Dosing may vary based on formulation and intended effect.
## Pediatric Dosing
* **Constipation:**
* **Ages 1-5 years:** 5 mL by mouth once daily.
* **Ages 6-12 years:** 10 mL by mouth once daily.
* **Ages >12 years:** 10 mL to 20 mL by mouth once daily.
* *Note: Dosing in children may require specific product instructions or clinical judgment.*
## Dose Adjustments
No dose adjustments are typically required for hepatic or renal impairment.
## Contraindications
* Abdominal pain, nausea, vomiting, or other symptoms of appendicitis or undiagnosed abdominal conditions.
* Intestinal obstruction.
* Hypersensitivity to liquid paraffin.
## Adverse Effects
* Abdominal cramping, bloating, diarrhea.
* Anal leakage (especially with higher doses).
* Lipoid pneumonia (if aspirated, particularly in infants or elderly, or with long-term use).
* Vitamin malabsorption (with chronic, high-dose use).
## Key Drug Interactions
* **Mineral oil can decrease the absorption of fat-soluble vitamins (A, D, E, K) and other lipophilic drugs.** Administer at least 2 hours apart from other oral medications.
## Monitoring
* Bowel movement frequency and consistency.
* Signs of vitamin deficiency with long-term, high-dose use.
* Signs of aspiration or lipoid pneumonia (rare, but increased risk with certain patient populations).
## Clinical Pearls
* Administer at bedtime to minimize disruption and reduce the risk of anal leakage during the day.
* Encourage adequate fluid intake concurrently with liquid paraffin.
* Avoid prolonged use due to potential for vitamin malabsorption and dependency.
* Caution is advised in infants, the elderly, and individuals with impaired swallowing due to the risk of aspiration and lipoid pneumonia.
***
**Disclaimer:** This information is intended for healthcare professionals. Always consult the most current prescribing information or product literature for complete details and to ensure it aligns with local protocols and patient-specific needs.