Liquid%252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a highly refined mineral oil used as a lubricant laxative. It coats the stool, making it softer and easier to pass. It is not absorbed by the body. ## Primary Indications Constipation. ## Adult Dosing * **Oral:** 10-30 mL once daily, usually at bedtime. * **Rectal (as an enema):** 100-120 mL per rectum. ## Pediatric Dosing * **Oral:** Dosing varies by age and is generally lower than adult doses. For example, 1-5 years: 5 mL once daily. 6-12 years: 10 mL once daily. Specific pediatric dosing should be guided by local protocols or a pediatrician. * **Rectal:** Not typically recommended for routine use in young children without medical supervision due to risk of complications. ## Dose Adjustments No dose adjustments are typically needed based on renal or hepatic impairment as it is not absorbed. ## Contraindications * Appendicitis or undiagnosed abdominal pain. * Intestinal obstruction. * Fecal impaction. * Nausea or vomiting. * Hypersensitivity to liquid paraffin. ## Adverse Effects * Anal leakage (most common), soiling of underwear. * Abdominal cramping, nausea, vomiting, diarrhea (especially with excessive doses). * Lipoid pneumonia (rare, associated with chronic aspiration, particularly in elderly or debilitated patients). * Vitamin malabsorption (long-term, high-dose use). ## Key Drug Interactions * **Mineral oil can decrease the absorption of fat-soluble vitamins (A, D, E, K) and certain medications absorbed orally** (e.g., digoxin, anticoagulants, oral contraceptives). Administer at least 2 hours apart from other oral medications and vitamin supplements. ## Monitoring * Bowel movements and frequency. * Signs of abdominal distension or obstruction. * Signs of lipid pneumonia (e.g., cough, fever, shortness of breath) in patients at risk. ## Clinical Pearls * Administer at bedtime to minimize anal leakage during the day. * Advise patients to use sanitary pads or protective underwear to manage potential anal leakage. * Long-term or excessive use should be avoided due to potential for vitamin deficiency and lipid pneumonia. * Not intended for short-term relief of constipation; longer-acting agents may be preferred. *** *This information is for educational purposes only and does not substitute for professional medical advice. Always verify current prescribing information and consult with a healthcare professional.*