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# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as an emollient and laxative. It works by softening stool and lubricating the intestinal tract, making it easier to pass.
## Primary Indications
* Constipation
## Adult Dosing
* **Oral:** 10-30 mL once daily or as needed. A maximum of 30 mL daily is typically recommended.
## Pediatric Dosing
* **Oral:** Dosing is highly variable and dependent on age and weight. Generally, **under 1 year:** 2.5-5 mL once daily. **1-5 years:** 5-10 mL once daily. **6-12 years:** 10-15 mL once daily. **Consult specific pediatric guidelines or a pediatrician for precise dosing.**
## Dose Adjustments
* No dose adjustments are typically needed based on renal or hepatic impairment.
## Contraindications
* Allergic reactions to liquid paraffin.
* Patients with intestinal obstruction or acute abdominal pain.
* Risk of aspiration (especially in infants and elderly).
## Adverse Effects
* Anal leakage or soiling (common, especially with higher doses).
* Abdominal cramping.
* Nausea or vomiting.
* Lipid pneumonia if aspirated.
## Key Drug Interactions
* **Mineral Oil (liquid paraffin) can decrease the absorption of fat-soluble vitamins (A, D, E, K) and other fat-soluble drugs (e.g., digoxin, oral anticoagulants).** Administer at least 2 hours apart from other medications.
## Monitoring
* Bowel movements (frequency, consistency).
* Signs of abdominal discomfort or obstruction.
## Clinical Pearls
* Administering liquid paraffin at bedtime may reduce the risk of anal leakage during waking hours.
* Advise patients to avoid lying down immediately after taking oral liquid paraffin to minimize aspiration risk.
* Long-term use is generally discouraged due to potential for vitamin malabsorption and dependency.
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*This information is intended for healthcare professionals. Always verify current prescribing information and consult with the appropriate resources before making clinical decisions.*
