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# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as an emollient and laxative. It works by coating the stool, making it easier to pass, and preventing water absorption from the colon.
## Primary Indications
* Constipation
## Adult Dosing
* **Laxative:** 10 mL to 30 mL by mouth once daily, typically at bedtime.
## Pediatric Dosing
* **Constipation:** Dosing varies by age and weight. Commonly, doses range from 5 mL to 20 mL by mouth once daily. Specific dosing should be determined by local protocol or a pediatrician.
## Dose Adjustments
* No specific dose adjustments are typically required for renal or hepatic impairment.
## Contraindications
* Appendicitis or unexplained abdominal pain.
* Intestinal obstruction.
* Fecal impaction.
* Hypersensitivity to liquid paraffin.
## Adverse Effects
* Anal leakage (especially with higher doses).
* Abdominal cramps.
* Nausea.
* Vomiting.
* Lipoid pneumonia (rare, from aspiration, particularly in the elderly or those with impaired swallowing reflexes).
## Key Drug Interactions
* **Fat-soluble vitamins (A, D, E, K):** Long-term use may reduce the absorption of fat-soluble vitamins.
* **Other laxatives:** Concurrent use may lead to electrolyte imbalances.
## Monitoring
* Bowel movements (frequency and consistency).
* Signs of abdominal pain or distension.
* Monitor for anal leakage.
## Clinical Pearls
* Administer at bedtime to minimize disruption and potential anal leakage during the day.
* Advise patients to drink plenty of fluids when using liquid paraffin.
* Caution is advised in patients with dysphagia or a history of aspiration due to the risk of lipoid pneumonia.
* Long-term daily use is generally not recommended.
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**Disclaimer:** This information is intended for clinical use and does not replace comprehensive prescribing information. Always verify current product labeling and consult with a qualified healthcare professional before initiating or modifying therapy.
