Liquid%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a mineral oil used as a laxative. It works by lubricating the stool and the intestinal walls, making defecation easier. ## Primary Indications * **Constipation:** For the relief of occasional constipation. ## Adult Dosing * **Oral:** 10 mL to 30 mL once daily, typically at bedtime. Do not exceed 30 mL in a 24-hour period. ## Pediatric Dosing * **Oral (6-12 years):** 5 mL once daily at bedtime. * **Oral (under 6 years):** Not generally recommended. Consult a pediatrician for appropriate management. ## Dose Adjustments No specific dose adjustments are typically required for hepatic or renal impairment, as absorption is minimal. ## Contraindications * **Abdominal pain, nausea, vomiting, or other symptoms of appendicitis or undiagnosed abdominal pain:** Use may mask serious underlying conditions. * **Patients with difficulty swallowing:** Risk of aspiration and lipoid pneumonia. * **Hypersensitivity to liquid paraffin.** ## Adverse Effects * **Gastrointestinal:** Anal leakage, abdominal cramping, diarrhea. * **Aspiration:** Can lead to lipoid pneumonia, especially in the elderly or those with impaired gag reflexes. * **Malabsorption:** Long-term, high-dose use may interfere with the absorption of fat-soluble vitamins (A, D, E, K). ## Key Drug Interactions * **Fat-soluble vitamins:** May decrease absorption. * **Steroids:** May decrease absorption. * **Certain medications taken orally:** May decrease absorption due to reduced transit time or coating of the intestinal mucosa. Separate administration by at least 2 hours. ## Monitoring * Monitor for relief of constipation. * Assess for signs of anal leakage or abdominal cramping. * Consider monitoring for fat-soluble vitamin deficiencies with prolonged, regular use. ## Clinical Pearls * Administer at bedtime to reduce the likelihood of anal leakage during the day. * Avoid administering in a supine position or to individuals with impaired swallowing to minimize the risk of aspiration. * Not intended for chronic use; regular bowel habits should be encouraged through diet and lifestyle modifications. * The risk of lipoid pneumonia is a serious concern, particularly in vulnerable populations. *** **Disclaimer:** This information is intended for healthcare professionals. Always consult the most current prescribing information or official guidelines for complete details and to verify specific recommendations before initiating treatment.