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# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as a laxative. It lubricates the intestinal walls, softening stool and facilitating its passage. It is poorly absorbed from the gastrointestinal tract.
## Primary Indications
Constipation.
## Adult Dosing
* **Oral:** 10-20 mL once daily or as needed. Maximum dose typically not specified but should be used cautiously.
## Pediatric Dosing
* **Oral:**
* **1-12 years:** 5-10 mL once daily or as needed.
* **Under 1 year:** Use with caution and under medical supervision. Dosing is variable and typically starts at 2.5-5 mL once daily.
## Dose Adjustments
No dose adjustments are typically required for renal or hepatic impairment.
## Contraindications
* Hypersensitivity to liquid paraffin.
* Appendicitis or symptoms of acute abdominal pain.
* Intestinal obstruction or fecal impaction.
* Co-administration with docusate sodium (risk of pulmonary toxicity).
* Use in patients at risk of aspiration (e.g., elderly, impaired gag reflex, supine position) due to risk of lipoid pneumonia.
## Adverse Effects
* Anal leakage (especially with higher doses).
* Abdominal cramps.
* Nausea, vomiting.
* Lipoid pneumonia (if aspirated).
* Decreased absorption of fat-soluble vitamins (A, D, E, K) with chronic, high-dose use.
## Key Drug Interactions
* **Docusate Sodium:** Contraindicated due to increased risk of pulmonary toxicity.
* **Fat-soluble vitamins (A, D, E, K):** Absorption may be decreased. Advise patients to separate administration by at least 2 hours.
## Monitoring
* Bowel movements and consistency.
* Signs of abdominal discomfort or obstruction.
* Signs of aspiration (coughing, shortness of breath).
## Clinical Pearls
* Administer undiluted or mixed with a small amount of liquid.
* Avoid use in the supine position or in patients with impaired swallowing reflexes due to the risk of aspiration and lipoid pneumonia.
* Should not be taken immediately before lying down.
* Long-term, regular use is generally not recommended due to potential for electrolyte imbalance and dependency. Intermittent use for symptomatic relief is preferred.
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**Disclaimer:** This information is intended for healthcare professionals. Always consult the most current prescribing information and local protocols before making clinical decisions. Dosing and recommendations may vary.
