Liquid%252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a mineral oil used as an emollient and laxative. It acts by lubricating the stool and the intestinal wall, softening fecal matter and easing defecation. ## Primary Indications * Constipation ## Adult Dosing * **Oral:** 10 mL to 30 mL once daily, typically at bedtime. * **Rectal (as enema):** May be used rectally for fecal impaction, follow specific product instructions or local protocol. ## Pediatric Dosing * **Oral:** * **1-5 years:** 5 mL once daily. * **6-12 years:** 10 mL once daily. * **Over 12 years:** Same as adult dosing. * *Note: Use in infants and very young children should be under medical supervision due to the risk of aspiration.* ## Dose Adjustments No dose adjustments are typically needed for renal or hepatic impairment. ## Contraindications * Known hypersensitivity to liquid paraffin. * Patients with appendicitis, intestinal obstruction, or fecal impaction. * Prolonged use is generally not recommended. * Caution in individuals with difficulty swallowing due to risk of aspiration, especially in the elderly or those with neurological impairment. ## Adverse Effects * **Common:** Abdominal cramps, bloating, diarrhea, anal leakage. * **Rare:** Lipid pneumonia (if aspirated), vitamin malabsorption (with chronic use). ## Key Drug Interactions * **Mineral Oil (Oral):** May decrease the absorption of fat-soluble vitamins (A, D, E, K) and concurrently administered oral medications, particularly those with sustained-release formulations. Separate administration by at least 2 hours. ## Monitoring * Monitor for effectiveness (bowel movements). * Assess for signs of anal leakage, cramping, or diarrhea. * If used chronically, consider monitoring for vitamin deficiency. ## Clinical Pearls * Administer at bedtime to minimize anal leakage during the day. * Avoid concurrent use with fat-soluble vitamins or oral medications that require consistent absorption. * Educate patients about the potential for anal leakage and the importance of not lying down immediately after administration due to aspiration risk. * Long-term, daily use is not recommended due to potential complications. --- ***Disclaimer:** This information is intended for healthcare professionals. Always verify current prescribing information and consult with a qualified healthcare provider for any medical advice or treatment decisions.*