Liquid%25252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a mineral oil used as a laxative. It lubricates the fecal mass and intestinal walls, softening stool and easing its passage. ## Primary Indications Constipation. ## Adult Dosing * **Oral:** 10 mL to 30 mL once daily, typically at bedtime. ## Pediatric Dosing * **Oral:** Dosing varies significantly by age and weight. Consult current pediatric guidelines or a pediatrician. A common starting point for children aged 6-12 years might be 5 mL to 10 mL once daily. Doses for younger children are generally lower and require extreme caution. ## Dose Adjustments No specific dose adjustments are typically required for renal or hepatic impairment. Dosing should be based on clinical response and patient tolerance. ## Contraindications * Appendicitis or undiagnosed abdominal pain. * Intestinal obstruction or perforation. * Inability to swallow without risk of aspiration. * Concurrent use of docusate sodium (increased absorption of liquid paraffin). ## Adverse Effects * Anal leakage (especially with higher doses). * Abdominal cramping or discomfort. * Nausea. * Lipoid pneumonia (rare, associated with aspiration, particularly in the elderly or those with swallowing difficulties). * Vitamin malabsorption (with chronic, long-term use). ## Key Drug Interactions * **Docusate sodium:** Co-administration may increase the absorption of liquid paraffin, leading to potential systemic effects. * **Fat-soluble vitamins (A, D, E, K):** Chronic use may impair absorption. Separate administration by at least 2 hours. ## Monitoring * Bowel movements (frequency, consistency). * Signs of anal leakage or discomfort. * For chronic use, monitor for signs of vitamin deficiency. ## Clinical Pearls * Administer undiluted or mixed with water or juice. * Take at bedtime to minimize anal leakage. * Avoid use in patients with dysphagia or a history of aspiration. * Long-term daily use is generally not recommended due to potential for vitamin malabsorption and dependency. *** *This information is intended for healthcare professionals. Always consult the most current prescribing information and institutional protocols before making any clinical decisions.*