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# Liquid Paraffin
## Overview
Liquid paraffin is a highly refined mineral oil. It acts as an emollient and lubricant.
## Primary Indications
* Constipation
## Adult Dosing
* 10-20 mL once daily or in divided doses. Maximum dose is typically 40 mL daily.
## Pediatric Dosing
* **Ages 1-12 years:** 5-10 mL once daily or in divided doses.
* **Under 1 year:** Use is generally not recommended due to increased risk of aspiration. If used, doses are typically 2.5-5 mL once daily, under strict medical supervision.
## Dose Adjustments
No dose adjustments are typically required for renal or hepatic impairment.
## Contraindications
* Intestinal obstruction
* Nausea, vomiting, or abdominal pain of unknown etiology
* Hypersensitivity to liquid paraffin
* Increased risk of aspiration (e.g., in patients with swallowing difficulties, elderly, very young children, or those with impaired gag reflex).
## Adverse Effects
* Diarrhea, abdominal cramping
* Nausea, vomiting
* Anal leakage, soiling
* Lipid pneumonia (with chronic aspiration)
* Reduced absorption of fat-soluble vitamins (with chronic use)
## Key Drug Interactions
* May decrease the absorption of fat-soluble vitamins (A, D, E, K) and other lipophilic drugs when taken concurrently. Separate administration by at least 2 hours.
## Monitoring
* Bowel movements for efficacy and frequency.
* Signs of abdominal discomfort or obstruction.
* Monitor for anal leakage.
## Clinical Pearls
* Administer undiluted.
* Do not administer immediately before lying down.
* Avoid coadministration with other medications that could be absorbed less effectively.
* Long-term, regular use is generally discouraged due to potential adverse effects.
* Use with extreme caution in patients at risk of aspiration.
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_Please verify the current prescribing information for the most up-to-date and complete details. This information is for educational purposes only and does not constitute medical advice._
