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# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as an emollient and a laxative. It works by lubricating the intestinal tract, softening the stool, and promoting bowel movements.
## Primary Indications
* Constipation
## Adult Dosing
* **Laxative:** 10-30 mL by mouth once daily, usually at bedtime. The dose may be adjusted based on response.
## Pediatric Dosing
* **Under 1 year:** Not generally recommended due to risk of aspiration.
* **1-5 years:** 5 mL by mouth once daily.
* **6-12 years:** 10 mL by mouth once daily.
* **Over 12 years:** Same as adult dosing.
* *Dosing may vary based on local protocol and product labeling.*
## Dose Adjustments
No specific dose adjustments are typically required for hepatic or renal impairment.
## Contraindications
* Hypersensitivity to liquid paraffin.
* Appendicitis or undiagnosed abdominal pain.
* Intestinal obstruction.
* Difficulty swallowing (due to risk of aspiration).
## Adverse Effects
* Anal leakage (especially with higher doses).
* Abdominal cramping.
* Nausea.
* Vomiting.
* Lipoid pneumonia (rare, with chronic aspiration).
* Fat-soluble vitamin malabsorption (with chronic use).
## Key Drug Interactions
* **Fat-soluble vitamins (A, D, E, K):** Long-term use may decrease absorption.
* **Docusate:** Concurrent use may increase absorption of liquid paraffin.
## Monitoring
* Bowel movement frequency and consistency.
* Signs of abdominal pain or distension.
* Signs of aspiration.
## Clinical Pearls
* Administer at bedtime to minimize daytime inconvenience from potential anal leakage.
* Avoid taking shortly before lying down to reduce aspiration risk.
* Do not use for prolonged periods without medical advice due to potential for vitamin malabsorption and dependence.
* Ensure adequate fluid intake when using laxatives.
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*This information is intended for healthcare professionals. Always consult the most current prescribing information and institutional protocols before making clinical decisions.*
