Please check your internet connection and try again.
# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as an emollient and a laxative. It works by softening the stool and lubricating the intestinal tract, making defecation easier.
## Primary Indications
* Constipation (short-term relief)
* Prevention of fecal impaction
* Softering of stool for patients with hemorrhoids or anal fissures
## Adult Dosing
* **Laxative:** 10-30 mL once daily, usually at bedtime. Maximum dose is typically 30 mL per day.
* **Emollient/Stool Softener:** Dosing can vary; consult product labeling or local protocol.
## Pediatric Dosing
* **Constipation (short-term relief):**
* **Children 6-12 years:** 5-10 mL once daily.
* **Children 1-5 years:** 5 mL once daily.
* **Under 1 year:** Not generally recommended without physician guidance.
## Dose Adjustments
No specific dose adjustments are typically required based on renal or hepatic impairment.
## Contraindications
* Appendicitis or symptoms of appendicitis
* Intestinal obstruction
* Fecal impaction
* Nausea, vomiting, or abdominal pain of unknown origin
* Hypersensitivity to liquid paraffin
## Adverse Effects
* Diarrhea
* Abdominal cramping
* Nausea
* Anal leakage (especially with higher doses or if taken while lying down)
* Lipoid pneumonia (rare, associated with chronic aspiration, particularly in debilitated or elderly individuals)
* Malabsorption of fat-soluble vitamins (A, D, E, K) with chronic, long-term use.
## Key Drug Interactions
* **Fat-soluble vitamins (A, D, E, K):** Chronic use of liquid paraffin can decrease their absorption. Consider separate administration or vitamin supplementation.
* **Other medications:** Liquid paraffin can potentially decrease the absorption of other orally administered drugs due to its lubricating and binding properties. Separate administration by at least 2 hours.
## Monitoring
* Bowel movements (frequency, consistency)
* Signs of abdominal pain, distension, or obstruction
* Anal leakage
* Signs of vitamin deficiency with chronic use.
## Clinical Pearls
* Liquid paraffin should be used for short-term relief of constipation only, generally not exceeding one week, unless directed by a healthcare professional.
* Avoid administration with meals or immediately before lying down to minimize the risk of aspiration and lipoid pneumonia.
* Adequate fluid intake is essential when using laxatives.
* Chronic use can lead to dependence on laxatives and is not recommended.
* Emphasize to patients that anal leakage can occur, especially if the dose is too high or taken without adequate fluid.
***
**Disclaimer:** This information is intended for healthcare professionals. Always consult the most current prescribing information and local protocols before making clinical decisions.
