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# Liquid Paraffin
## Overview
Liquid paraffin is a mineral oil used as a lubricant laxative. It works by softening the stool and coating the intestinal wall, making defecation easier.
## Primary Indications
* Constipation
## Adult Dosing
* 10-30 mL once daily or divided twice daily.
* Maximum dose not clearly established but typically around 30-45 mL daily.
## Pediatric Dosing
* **1-5 years:** 2.5-5 mL once daily.
* **5-10 years:** 5-10 mL once daily.
* **Over 10 years:** Same as adult dosing.
* *Dosing may vary; consult local pediatric guidelines.*
## Dose Adjustments
No dose adjustments are typically required for renal or hepatic impairment.
## Contraindications
* Abdominal pain of unknown origin.
* Nausea or vomiting.
* Bowel obstruction.
* Inability to swallow without aspiration risk.
* Concurrent use of docusate sodium.
## Adverse Effects
* Anal leakage (especially with higher doses).
* Abdominal cramping.
* Nausea.
* Vomiting.
* Diarrhea.
* Pruritus.
* **Long-term use:** Can lead to vitamin malabsorption (A, D, E, K) and lipoid pneumonia if aspirated.
## Key Drug Interactions
* **Mineral oil can decrease the absorption of fat-soluble vitamins (A, D, E, K).**
* **Mineral oil can decrease the absorption of other medications taken orally.** Separate administration by at least 2 hours.
## Monitoring
* Bowel movements (frequency, consistency).
* Signs of electrolyte imbalance if diarrhea occurs.
* Signs of aspiration (coughing, choking) if risk factors are present.
## Clinical Pearls
* Administer at bedtime to minimize daytime anal leakage.
* Avoid use in the elderly or debilitated patients due to aspiration risk.
* Long-term use should be discouraged.
* Ensure patient is able to swallow safely.
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*Disclaimer: This information is intended for healthcare professionals. Always consult the most current prescribing information and local protocols before making clinical decisions.*
