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# Citral ## Overview Citral is a mixture of two acyclic monoterpene **geraniol** and **nerol** isomers. It is primarily used as a flavoring agent and fragrance. There is limited clinical data for its use as a therapeutic agent. ## Primary Indications There are no FDA-approved indications for citral. It is commonly found in: * Flavoring agent in food and beverages. * Fragrance component in cosmetics and personal care products. ## Adult Dosing * **Flavoring:** Generally recognized as safe (GRAS) by the FDA for use as a flavoring agent in food. Specific amounts vary widely based on product formulation and are typically at low concentrations. * **Fragrance:** Used in various cosmetic and personal care products at concentrations typically below 1%. ## Pediatric Dosing No specific pediatric dosing recommendations exist as citral is not used therapeutically in children. It is present in many consumer products, and exposure is via ingestion (food/drink) or dermal contact (cosmetics). ## Dose Adjustments Not applicable for its common uses. ## Contraindications * Known hypersensitivity to citral. ## Adverse Effects * **Dermal:** Potential for skin sensitization and allergic contact dermatitis, particularly in fragrance applications. * **Oral:** Generally considered safe at levels used in food. High concentrations may cause gastrointestinal upset. ## Key Drug Interactions No significant drug interactions have been established for citral in its typical uses. ## Monitoring Not applicable for its common uses. For individuals with known sensitivity, monitor for signs of allergic reaction. ## Clinical Pearls * Citral is a common allergen found in essential oils like lemongrass and lemon verbena. * Its use is primarily in consumer products, not as a prescription medication. *** **Disclaimer:** This information is intended for healthcare professionals. It is essential to consult the most current prescribing information and relevant literature for definitive guidance. Local protocols and guidelines may influence clinical decisions.