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# Citral
## Overview
Citral is a mixture of two acyclic monoterpene geometric isomers, geranial (trans-citral) and neral (cis-citral). It is found in the oils of many plants, including lemon myrtle, lemon verbena, and lemongrass. Citral is used in flavorings, fragrances, and as a precursor for synthesizing other compounds.
## Primary Indications
Citral does not have FDA-approved indications as a pharmaceutical agent. It is primarily used in the food and fragrance industries.
## Adult Dosing
Not applicable, as citral is not an FDA-approved medication.
## Pediatric Dosing
Not applicable.
## Dose Adjustments
Not applicable.
## Contraindications
There are no established contraindications for the use of citral in a pharmaceutical context, as it lacks approved indications. However, individuals with known hypersensitivity to citral or its components should avoid exposure.
## Adverse Effects
When used in topical products or ingested in food, citral is generally recognized as safe (GRAS) by the FDA in typical concentrations. However, concentrated citral can be a skin irritant and a potential sensitizer, leading to allergic contact dermatitis in susceptible individuals. Ingestion of very large amounts may cause gastrointestinal upset.
## Key Drug Interactions
No significant drug interactions are established for citral in a pharmaceutical context due to its lack of approved indications.
## Monitoring
Not applicable.
## Clinical Pearls
Citral's primary applications are in flavoring and fragrance. Its potential as a skin irritant and sensitizer is the most significant safety consideration outside of its intended industrial uses.
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*Disclaimer: This information is intended for healthcare professionals. It is essential to consult the most current prescribing information and relevant literature before making any clinical decisions. Dosing and indications may vary based on local protocols and individual patient factors.*
