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# Citral ## Overview Citral is a mixture of two acyclic monoterpene geometric isomers, geranial (trans-citral) and neral (cis-citral). It is commonly found in the oils of various plants, such as lemon myrtle, lemon verbena, and citrus fruit peels. It is primarily used in traditional medicine and as a flavoring agent. ## Primary Indications * Historically used for digestive complaints and as a mild sedative. * Its use as a therapeutic agent in modern Western medicine is limited and not well-established by robust clinical trials for specific indications. ## Adult Dosing There is no standard, evidence-based dosing regimen for citral in adults. Doses used in traditional or herbal preparations vary widely. ## Pediatric Dosing No established pediatric dosing. Due to lack of safety data, use in children is not recommended. ## Dose Adjustments Not applicable due to lack of standardized dosing and indications. ## Contraindications * Hypersensitivity to citral. ## Adverse Effects * Skin irritation and allergic reactions (contact dermatitis) are the most commonly reported adverse effects, especially with topical application. * Gastrointestinal upset may occur with oral ingestion. * Limited data exists on systemic toxicity. ## Key Drug Interactions * No significant drug interactions have been well-documented in the literature. However, caution should be exercised if used concurrently with other substances that may cause gastrointestinal upset or skin irritation. ## Monitoring * Monitor for signs of skin irritation or allergic reaction with topical use. * Monitor for gastrointestinal symptoms with oral use. ## Clinical Pearls * Citral is primarily recognized for its scent and flavor. Its therapeutic efficacy for most conditions is not supported by strong scientific evidence. * When used in topical preparations, dilution is often recommended to minimize the risk of skin sensitization. * The safety and efficacy of citral for specific medical conditions are largely unproven. *** *Disclaimer: This information is intended for healthcare professionals. It is essential to consult the most current prescribing information and relevant literature before making clinical decisions. Dosing and safety information may vary based on product formulation, route of administration, and individual patient factors. This document does not substitute for professional medical advice.*