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# Citral ## Overview Citral is a mixture of two acyclic monoterpene geometric isomers, geranial (trans-citral) and neral (cis-citral). It is found in the oils of many plants, including lemon, lime, and lemongrass. ## Primary Indications Citral is primarily used as a flavoring agent and fragrance component in various consumer products. Its therapeutic use is limited, with some research exploring its potential anti-inflammatory, anxiolytic, and antimicrobial properties, but these are not established clinical indications. ## Adult Dosing There is no established adult dosing for citral for therapeutic purposes. Its use in consumer products is typically at low concentrations for flavoring or fragrance. ## Pediatric Dosing There is no established pediatric dosing for citral for therapeutic purposes. ## Dose Adjustments Not applicable for therapeutic use due to lack of established dosing. ## Contraindications * Hypersensitivity to citral. ## Adverse Effects * **Dermal:** Skin irritation, allergic contact dermatitis (most common). * **Gastrointestinal:** Nausea, vomiting (rare, typically with high oral intake). * **Respiratory:** Respiratory irritation (with inhalation of high concentrations). ## Key Drug Interactions No significant drug interactions have been established for citral in a therapeutic context. ## Monitoring Not applicable for therapeutic use. For individuals using products containing citral who experience allergic reactions, monitoring for resolution of symptoms is advised. ## Clinical Pearls * Citral is a common allergen, particularly in fragrances. Individuals with known sensitivities should avoid products containing citral. * Research into therapeutic applications of citral is ongoing but not sufficient for clinical practice. *** **Disclaimer:** This information is intended for healthcare professionals and is not a substitute for professional medical advice. Always consult the most current prescribing information and relevant literature before making any treatment decisions. Dosing and indications can vary based on specific product formulations and local protocols.