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# Citral ## Overview Citral is a mixture of two acyclic monoterpene geometric isomers, geranial and neral. It is a component of many essential oils and is often used for its fragrance and flavoring properties. It is not an FDA-approved medication and is primarily available as a dietary supplement or cosmetic ingredient. ## Primary Indications Citral is not indicated for any specific medical condition by regulatory bodies like the FDA. It is primarily used in the flavor and fragrance industries. Some *in vitro* and animal studies suggest potential anti-inflammatory, antioxidant, and antimicrobial properties, but these are not established clinical indications. ## Adult Dosing There is no established or recommended adult dosing for citral as a therapeutic agent. Its use is typically dictated by product formulation for flavoring or fragrance. ## Pediatric Dosing There is no established or recommended pediatric dosing for citral as a therapeutic agent. ## Dose Adjustments Not applicable as there are no established therapeutic doses. ## Contraindications * Hypersensitivity to citral or components of the product it is in. ## Adverse Effects When used in topical products, citral can cause skin irritation, allergic contact dermatitis, and photosensitivity in some individuals. Oral ingestion may cause gastrointestinal upset. Systemic toxicity data is limited. ## Key Drug Interactions No significant drug interactions are established for citral in a therapeutic context. ## Monitoring Not applicable as there are no established therapeutic uses or doses. ## Clinical Pearls Citral is generally recognized as safe (GRAS) for use as a flavoring agent by the FDA. However, its potential to cause skin sensitization should be considered, especially in cosmetic formulations or when handled in concentrated forms. --- **Disclaimer:** This information is intended for healthcare professionals and is based on available data. It is crucial to consult the most current prescribing information and relevant literature for definitive guidance. This information does not replace professional judgment or institutional protocols.