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# Citral ## Overview Citral is a naturally occurring acyclic monoterpene aldehyde found in the oils of many plants, including lemon myrtle, lemon verbena, and lemongrass. It is a mixture of two geometric isomers: geranial (trans-citral) and neral (cis-citral). ## Primary Indications Citral is primarily used for its aromatic properties in fragrances and flavorings. It has limited established therapeutic indications in conventional Western medicine. Some research explores its potential antimicrobial, anti-inflammatory, and analgesic properties, but these are not widely clinically applied. ## Adult Dosing There is no standardized adult dosing for citral in a therapeutic context due to its lack of approved pharmaceutical indications. Its use is typically confined to flavorings and fragrances where concentration is dictated by product formulation. ## Pediatric Dosing There is no established pediatric dosing for citral. ## Dose Adjustments Dose adjustments are not applicable as there are no established therapeutic doses. ## Contraindications * Hypersensitivity to citral or components of fragrance/flavor formulations containing citral. * Inhalation of concentrated citral may cause respiratory irritation. ## Adverse Effects Adverse effects are generally associated with topical application or ingestion of high concentrations. * **Topical:** Skin irritation, allergic contact dermatitis. * **Inhalation:** Respiratory irritation, bronchospasm (especially in individuals with asthma). * **Ingestion:** Gastrointestinal upset (nausea, vomiting, diarrhea) at very high doses. ## Key Drug Interactions No significant drug interactions are established for citral in a therapeutic context. Potential for additive skin irritation if used concurrently with other topical irritants. ## Monitoring Monitoring is not typically required for citral when used in approved cosmetic or food applications. If used in experimental settings, monitor for signs of skin or respiratory irritation. ## Clinical Pearls * Citral is a common component of essential oils and is responsible for citrus-like aromas. * Its primary use is in the flavor and fragrance industry. * Limited clinical evidence supports its use for specific medical conditions. *** **Disclaimer:** This information is intended for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional and refer to the most current prescribing information for any medication before making any treatment decisions.